What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of 11C-JNJ-42491293, A Novel Radioligand for mGluR2

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

What we see and what we do not see in health care

What we see and what we do not see in heath care Fourteen years ago, US Inspector General and the Department of Health and Human Services conduced a detailed analysis of money outflow from the Medicare and Medic-aid federal health care programs; their findings shocked the nation: US $23 billion was lost annually to different forms of fraud and corruption, reaching 14% of the total health budget...

"What We Feel, and What Doth us Befall": A Study of Letter Motif in Macbeth 

The present essay is an attempt to scrutinize Macbeth's letter to Lady Macbeth formalistically with much care and seek hints which may lead us back and forth to understand what befell before and after the composition and emission of the letter. The letter seems to help us plunge into Macbeth's consciousness, and of course later to that of Lady Macbeth; it is a transparent aid to perceive the hi...

Thalassemia Intermedia; Folic Acid and Vitamin B12 Supplementation. What We Know and What is Needed?

This study presented a mini review on folic acid deficiency and recommendations for its supplementation in thalassemia intermedia (TI). TI is a clinical condition which lies between thalassemia major and thalassemia minor. Although TI patients may not need regular blood transfusion, precise diagnosis and management are critical for the prevention of clinical complications and quality of life im...

Do We Know What We Do not Know? A Response to Celine Bonnet